Officials from ministries of Health, Finance pause for pictures with the US Ambassador to Uganda, William Popp (2nd L), following the signing of the MOU today, 10th December 2025
HABARI DAILY I Kampala, Uganda I Uganda and the United States of America have signed a five-year, $2.3 billion Memorandum of Understanding (MOU) to strengthen Uganda’s health system, expand disease surveillance, and boost global health security.
The U.S. will provide $1.7 billion, while Uganda commits to increasing domestic health spending by over $500 million from 2026 to 2030.
William Popp, the U.S. Ambassador to Uganda said the agreement marks “a significant shift toward promoting self-reliance through strong community health systems, clear performance metrics, and data systems that will prevent and stop outbreaks from threatening Uganda, the United States, and the world.”
Finance Minister Matia Kasaija welcomed the partnership, noting that the collaboration “will not only result in disease-specific outcomes but also improvements in national systems, institutions, and workforce capacity.”
The MOU covers priority areas including HIV/AIDS, TB, malaria, maternal and child health, polio eradication, emergency preparedness, digitization, and support for faith-based health providers. It also provides for gradual transition of U.S.-funded health workers and procurement of health commodities to the Government of Uganda.
Health Minister Dr. Jane Ruth Aceng described the deal as “a strategic, sovereign-driven partnership” that aligns with Uganda’s Vision 2040, adding that “Uganda’s sovereignty over its biological resources and health data is non-negotiable.”
The agreement is one of the largest bilateral health investments in Uganda and builds on more than 60 years of U.S.–Uganda cooperation.
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